Download Abnormalities in puberty : scientific and clinical advances by H.A. Delemarre-van de Waal, P.-E. Mullis PDF

By H.A. Delemarre-van de Waal, P.-E. Mullis

This booklet on abnormalities in puberty offers an outline at the most up-to-date wisdom at the mechanisms of the developmental strategies of puberty. even if the precise mechanisms of reawakening of the GnRH pulse generator on the onset of puberty nonetheless need to be elucidated, many genetic and environmental elements were pointed out to play a tremendous function. subject matters mentioned in person chapters contain the endocrine and metabolic matters regarding the 'developmental beginning of grownup ailment' speculation and polycystic ovary syndrome in addition to abnormalities in GnRH controlling genes, GnRH-secreting hamartoma as a version for the onset of puberty, adventure at the program of GnRH analogues within the therapy of critical precocious puberty, and the psychosocial results of an early puberty. This quantity presents the paediatrician, endocrinologist, gynaecologist and physician with underlying details in addition to functional tokens on tips on how to deal with many of the stipulations of a disturbed means of puberty.

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Br J Obstet Gynaecol 1996:103:814–817. Ibanez L, Ferrer A, Marcos MV, Hierro FR, De Zegher F: Early puberty: Rapid progression and reduced final height in girls with low birth weight. Pediatrics 2000;106:E72. Albertsson-Wikland K, Karlberg J: Natural growth in children born small for gestational age with and without catch-up growth. Acta Paediatrica Suppl 1994;399:64–70. Powls A, Botting N, Cooke RW, Pilling D, Marlow N: Growth impairment in very low birthweight children at 12 years: Correlation with perinatal and outcome variables.

Harding JE: The nutritional basis of the fetal origins and adult disease. Int J Epidemiol 2001;30: 15–23. Lucas A: Programming by early nutrition in man; in Bock GR, Whelen J (eds): The Childhood Environment and Adult Disease. Chichester, Wiley, 1991, pp 38–55. Lucas A: Role of nutritional programming in determining adult morbidity. Arch Dis Child 1994;71:288–290. Strauss RS: Effects of the intrauterine environment on childhood growth. Br Med Bull 1997;53: 81–95. Barker DJP: Fetal nutrition and cardiovascular disease in later life.

6). 2 kg/m2. Weissenbruch/Engelbregt/Veening/Delemarre-van de Waal 20 Table 1. 001 AGA vs. SGA. Table 2. 1 24 0 29 0 7 15 6 20 CA ϭ Calendar age; BA ϭ bone age. Pubertal Development At the first visit all children were prepubertal (table 2). 1 vs. 003). 5 Age at follow-up (yr) Fig. 1. Breast stage at follow-up in girls born SGA and girls born AGA. 5 years later, 20 of 26 SGA children and 15 out of 22 AGA children were pubertal. 1 vs. 004). 6 vs. 1). SGA girls have a more advanced breast stage at a certain calendar age than their AGA controls (fig.

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