Download An update on glomerulopathies : clinical and treatment by Sharma S Prabhakar PDF

By Sharma S Prabhakar

Show description

Read Online or Download An update on glomerulopathies : clinical and treatment aspects PDF

Best clinical books

Small Animal Clinical Diagnosis by Laboratory Methods, 5th Edition

A short consultant to adequately opting for and examining laboratory checks, Small Animal medical analysis through Laboratory tools, fifth variation is helping you employ your in-house lab or your forte reference lab to successfully make actual diagnoses with out working a plethora of pointless and low-yield checks.

Clinical Obesity in Adults and Children, Second Edition

Hugely counseled within the 2006 British clinical organization e-book Awards (Endocrinology)This moment variation brings jointly greater than 20 across the world well-known specialists within the box to supply a well timed overview of present wisdom. The textual content continues to be a useful source for all healthcare execs fascinated about the care of sufferers who're overweight.

Handbook of Clinical Nutrition and Stroke

Guide of scientific meals and Stroke is a complete reference on nutrients for the multidisciplinary workforce taking care of stroke sufferers. focusing on physicians, nurse practitioners, medical dietitians, and complex allied future health and scientific scholars, this quantity offers an creation at the varieties of stroke, linked danger elements, and uniquely featured worldwide views on stroke.

Clinical Use of Antiviral Drugs

Antiviral chemotherapy has come of age, and, after an preliminary sluggish professional­ gress, the advance of recent antiviral brokers has proceeded at a extra quick speed and the views for his or her medical use have elevated significantly. Now, 25 years after the 1st antiviral assay (idoxuridine) was once brought within the hospital, it's becoming to commemorate the start of the antivirals' period.

Additional info for An update on glomerulopathies : clinical and treatment aspects

Example text

The overexpression of transforming growth factor β (TGFβ) or its downstream proteins, the ‘Smads’ lead to glomerulosclerosis in animal models. Activation of the renin-angiotensin system upregulates TGFβ, which is considered to cause further progression of the disease (Harris RC et al. 2006). Angiogenic factors, like platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) seem to play a role in disease progression. This is based upon the rat remnant kidney model (RK model) experimental studies of progressive glomerulosclerosis.

Glomerular tip lesion patients may develop reversible acute renal failure, at the times of initial presentation when the degree of proteinuria, edema, hypoalbuminemia are at their peak. This behaves like minimal change disease and this rarely happens in any other forms of FSGS. Patients with glomerular tip lesion FSGS tend to be older white males in comparison to younger black males predominance in collapsing variant FSGS. Distinguishing between primary and secondary FSGS is important, since secondary FSGS should not respond to immunosuppressive therapy.

Nephrol. 5, 469–479 (2009); published online 7 July 2009 Wehrmann M, Bohle A, Bogenschutz O, et al. Long-term prognosis of chronic idiopathic membranous glomerulonephritis: An analysis of 334 cases with particular regard to tubulointerstitial changes. Clin Nephrol 1989;3:67. 2 Focal Segmental Glomerulosclerosis Dawinder S. Sohal and Sharma S. Prabhakar Department of Medicine, Texas Tech University Health Sciences Center USA 1. Introduction Focal segmental glomerulosclerosis (FSGS) as the name implies is a histopathological pattern of lesions, where the “focal” refers to, involving minority of glomeruli and the “segmental” refers to, involving a portion of the glomerular capillary tuft caused by injury to podocytes (Fig 1A).

Download PDF sample

Rated 4.51 of 5 – based on 41 votes