By Alexandre Psychoyos (auth.), Stanley R. Glasser, Joy Mulholland, Alexandre Psychoyos (eds.)
Early embryonic loss is a constant social and monetary worldwide challenge. In human populations the estimates of interruptions early in being pregnant variety from 35-60%. In animal husbandry (swine, ruminants) absolutely 30% of pregnancies fail to outlive early occasions of gestation. The futility linked to this persistant excessive threat is much more unsettling as a result of advances made in assisted reproductive know-how which, even though this very selective technique has further to our wisdom of embryo-endometrial interactions, has ended in a delivery cost of basically 14%. those reviews have instigated comparisons of the stay relative contributions of the embryo and the uterus to the result of being pregnant. those analyses have proven that we have got discovered considerably much less in regards to the position of the uterus in figuring out the result of both usual or assisted pregnancies. In 1979 a citation through George nook was once used to set the tone of a gathering that was once dedicated to dialogue of the mobile and molecular features of implantation. regardless of the proliferation in learn task which happened within the following 15 years our genuine realizing of the embryo move method has fallen in need of our expectancies. We use the nook citation, once more, to preface this symposium in order that we might bear in mind that the basic nature of the method which regulates embryo-endometrial interactions nonetheless escapes us.
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Extra info for Endocrinology of Embryo-Endometrium Interactions
Example text
B2 is abundant in the rat and mouse genomes which may contain as many as 10 copies of the gene. This gene is thought to be a retroposon, reverse transcribed from the RNA and inserted into adenosine rich regions of the genome (Rogers, 1985). Analysis of the B2 transcript revealed an open reading frame coding for a 40 amino acid protein, which has never been identified. , 1987). , 1990). When cells differentiate, cell division ceases and the B2 transcript is no longer expressed. Induction of B2 transcription in dividing cells is specific for this gene and is not the result of a general increase in RNA polymerase III activity (Carey and Singh, 1988).
Interactions between the human trophoblast cells and the extracellular matrix of the endometrium. Specific expression of a-galactose residues by invasive human trophoblastic cells. in: Trophoblast Invasion and Endometrial Receptivity. -W. D. Aplin, eds. (Trophoblast Research. Vol. 4). Plenum Medical Book Comp .. New York and London, pp. 159-177. Garbi. C .. TaccheUi. C .. H. , 1986. Change of inverted thyroid follicle into a spheroid after embedding in a collagen gel. Exp. Cell Res. 163:6377. R..
1992. Changes in histochemical distribution of cell surface heparan sulfate proteoglycan in mouse uterus during the estrous cycle and early pregnancy. Anal. Rec. 234:383-390. Psychoyos. A.. 1973. Endocrine control of egg implantation. in: Handbook of PhySiology. Sect. 7 (EndOCrinology). Vol. II (Female Reproductive System) Part 2. RO. Greep. ed .. American Physiological Society. Washington. pp. 187-215. Psychoyos. A.. 1986. Uterine receptivity for nidation. Ann. NY Acad. Sci. 476:36-42. Psychoyos.