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1978). J. Embryol. Exp. Morphol. ) Kaufman, . , and Gardner, R. L. (1974). J. Embryol. Exp. Morphol. 31, 635-642. Kaufman, . , and Sachs, L. (1975). J. Embryol. Exp. Morphol. 34, 645-655. Kaufman, . , and Sachs, L. (1976). J. Embryol. Exp. Morphol. 35, 179-190. Kaufman, . , and Surani, . A. H. (1974). J. Embryol. Exp. Morphol. 31, 5 1 3 - 5 2 6 . Kaufman, . , and Sachs, L. (1975). Nature (London) 254, 6 9 4 - 6 9 5 . Kaufman, . , Barton, S. C , and Surani, . A. H. (1977). Nature (London) 265, 5 3 - 5 5 .

1976). J. Embryol. Exp. Morphol. 35, 179-190. Kaufman, . , and Surani, . A. H. (1974). J. Embryol. Exp. Morphol. 31, 5 1 3 - 5 2 6 . Kaufman, . , and Sachs, L. (1975). Nature (London) 254, 6 9 4 - 6 9 5 . Kaufman, . , Barton, S. C , and Surani, . A. H. (1977). Nature (London) 265, 5 3 - 5 5 . 2 . Experimental Production of Parthenogenetic Embryos 47 Kaufman, . H . , Guc-Cubrilo, M . , and Lyon, M. F . (1978). ) Komar, A. (1973). / . Reprod. Fertil. 3 5 , 4 3 3 - 4 4 3 . Longo, F. J. (1974). Anat.

Under certain experimental conditions, this may be the commonest type of reaction seen. If, instead of extruding the second polar body, the egg divides into two equal blastomeres, this is referred to as "immediate cleavage" (Braden and Austin, 1954a). If cytokinesis does not occur at the completion of second meiosis, either two haploid pronuclei or a single diploid pronucleus develops within about 4 - 5 hours of activation. 27 2 . Experimental Production of Parthenogenetic Embryos Ovulated oocyte (Metaphase I I ) Second meiotic division Pronuclear e First s t a g cleovage Genetic constitution Uniform haploid Mosaic haploid Mosaic haploid Heterozygous diploid Heterozygous diploid I diploid pronucleus Fig.

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