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By Peter H. Dawson

Quadrupole Mass Spectrometry and Its functions presents a entire dialogue of quadrupoles and their functions. It proceeds from a normal rationalization of the motion of radiofrequency quadrupole fields to the outline in their usage in mass analyzers-such because the quadrupole mass filter out, the monopole, the third-dimensional quadrupole ion catch, and numerous time-of-flight spectrometers-and ultimately to the attribute functions of quadrupoles. A multi-author structure has been followed to supply broader-than-usual perspective within the publication. The e-book starts off via explaining the rules of operation of quadrupole units. those comprise ion trajectories and laptop simulations of functionality; analytical thought; numerical equipment of calculation of functionality, together with the lately built software of phase-space dynamics; and fringing fields and different box imperfections. next chapters supply layout and function reviews of the mass filter out, the monopole, ion traps, and time-of-flight tools; and describe components of program the place quadrupole units have made the best effect due to their specific benefits and drawbacks.

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Sample text

Curved quadrupoles [17] or curved sections [18] have also been used to avoid the problem but these forego the mechanical simplicity which is one of the mass filter's attractive features. When the applied potentials are small (or zero) as at the beginning of a mass scan, ions entering the filter may be transmitted even though their trajectories are mathematically unstable, just because of the weakness of the fields. This gives rise to an output signal at the beginning of a mass scan sometimes called the "zero blast".

A more detailed view of the overlap of the ellipses of Fig. 15. The area at the centre represents those initial conditions appropriate to 100% ion transmission. In the absence of fringing fields, the ion source emittance should be matched to the quadrupole acceptance, (a) x direction; (b) y direction. Mass filter sensitivity is most properly expressed in terms of the ellipses in phase-space scaled, as in Fig. 15, so that the maximum deflection is equal to r 0 . For 100% transmission, it is the overlap of the ellipses which is signifi­ cant.

At higher resolutions, such an aper­ ture was expected to give a smaller, perhaps triangular peak, with a decreased percentage transmission. , therefore, suggested that there are two operating ranges: (i) region I, low resolution, flat-topped peaks, with 100% ion transmission and intensity independent of resolution and (ii) region II, high resolution, triangular peaks, intensity decreases with resolution. It was expected that the peaks would be asymmetric because of the evident assymetry of Fig.

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