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By A. Wayne Meikle

Endocrine alternative remedy in scientific perform, an replace of Hormone Repla- ment treatment released by way of Humana Press in 1999, goals to help the endocrinologist, gynecologist, pediatrician, urologist, common physician, neurologist, neurosurgeon, p- chiatrist, generalist, and trainee in administration in their sufferers with hormonal defici- cies or altered hormonal synthesis or responses. Many new authors have further a number of new chapters, and the entire past chapters were up to date. Endocrine checking out used to diagnose endocrine problems and display screen hormone substitute treatment is reviewed. notwithstanding, distinct dialogue of body structure and pathophysiology isn't really an objective of this ebook, and those themes are coated in different volumes on endocrinology. even supposing nobody is taken into account knowledgeable in all components of endocrine substitute remedy, all of the authors the following have broad wisdom and adventure within the administration of sufferers with s- cific endocrine issues requiring hormone substitute therapy. even supposing a few variations of opinion exist between specialists in substitute remedy, every one author has tried to offer a balanced, impartial advice. while com- rable regimens exist, the authors have made this obvious to the reader who can then select the simplest remedy for the person sufferer. expense, healing effectiveness, and course of management are all vital issues in making the ultimate collection of alternative treatment.

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In: Narins RG, ed. Clinical Disorders of Fluid and Electrolyte Metabolism. McGraw Hill, New York, NY, 1994, pp. 81–100. 14. Robertson GL. Differential diagnosis of polyuria. Ann Rev Med 1988;39:425–442. 15. Elster AD. Modern imaging of the pituitary. Radiology 1993;187:1–14. 16. Richardson DW, Robinson AG. Desmopressin. Annu Intern Med 1985;103:228–239. 17. Fjellstad-Paulsen A, Paulsen O, d’Agay-Abensour L, Lundin S, Czernichow P. Central diabetes insipidus: oral treatment with dDAVP. Reg Pep 1993;45:303–307.

5). The only safe and effective way to treat this type of DI is to eliminate the excessive fluid intake. Unfortunately, there is currently no way to do this in either the psychogenic or the dipsogenic form of primary polydipsia. Therefore, the only treatment possible at present is to ameliorate some of the more annoying symptoms of nocturia and to educate the 36 Part I / Pituitary patient to prevent, recognize, and rapidly treat potentially serious complication of water intoxication. 1. The symptoms of nocturia can be relieved by small bedtime doses of DDAVP or lysine vasopressin.

Clin Sci 1982;63:525–532. 29. Shirley DG, Walter SJ, Laycock JF. The antidiuretic effect of chronic hydrochlorothiazide treatment in rats with diabetes insipidus: renal mechanisms. Clin Sci 1982;63:533–538. 30. Seckl JR, Dunger DB. Postoperative DI. Br Med J 1989;298:2,3. 31. Ciric I, Ragin A, Baumgartner C, Pierce D. Complications of transsphenoidal surgery: results of a national survey, review of the literature and personal experience. Neurosurgery 1997;40:225–236. 32. Seckl JR, Dunger DB. Neurohypophysial peptide function during early postoperative diabetes insipidus.

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